Document Detail


Free radical scavenging activity-guided isolation of a diterpenoid from Plectranthus punuctatus.
MedLine Citation:
PMID:  21941884     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Free radical scavenging activity-guided investigation of the acetone extract of Plectranthus punuctatus (L'Her) (Lamiaceae) resulted in the isolation of a novel diterpenoid 3,11,12,14,19-pentahydroxy-5,8,11,13-abietatraen-7-pyran[4,6]-16-dione whose structure was elucidated based on spectral evidence. The isolated compound showed a significant antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and deoxyribose degradation assays with IC50 values of 9.65 microg/mL and 5.25 microg/mL, respectively.
Authors:
Wossen Kebede; Daniel Bisrat; Kaleab Asres
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Natural product communications     Volume:  6     ISSN:  1934-578X     ISO Abbreviation:  Nat Prod Commun     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101477873     Medline TA:  Nat Prod Commun     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1229-32     Citation Subset:  IM    
Affiliation:
Aromatic, Medicinal and Bioenergy Research Case Team Laboratory, Institute of Ethiopian Agricultural Research, Addis Ababa, Ethiopia.
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