Document Detail


Free gingival grafts: graft shrinkage and donor-site healing in smokers and non-smokers.
MedLine Citation:
PMID:  20429648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: This prospective clinical study aims to evaluate the influence of cigarette smoking on free gingival graft (FGG) healing, by assessing FGG dimensional changes and donor-site wound healing. METHODS: Twelve non-smokers and 10 smokers treatment planned for FGG to augment keratinized tissue dimensions in the mandibular incisor area completed the study. All subjects received standardized FGG of same dimensions. Probing depth, gingival margin position, clinical attachment level, keratinized tissue (KT) width, gingival thickness, and FGG dimensions (width, length, and area) were assessed and recorded before surgery, and 7, 15, 30, 60, and 90 days postoperatively. The palatal donor area was evaluated for immediate bleeding and complete wound epithelialization. Differences between the two groups (smokers and non-smokers) were statistically analyzed. RESULTS: FGG dimensions changed significantly postoperatively. At 90 days postoperatively, FGG width, length, and area were respectively reduced by 31%, 22%, and 44% in non-smokers and by 44%, 25%, and 58% in smokers (no significant differences between groups; P >0.05). Significant KT increases were observed in both non-smokers and smokers (5.4 and 4.8 mm, respectively). Donor-site immediate bleeding was significantly more prevalent in non-smokers (75%) compared to smokers (30%) (P = 0.04). At 15 days postoperatively, donor-site complete epithelialization was much more prevalent in non-smokers (92%) than in smokers (20%) (P <0.002). CONCLUSION: Smoking alters FGG donor-site wound healing by reducing immediate bleeding incidence and by delaying epithelialization, although it does not have discernible effects on postoperative FGG dimensional changes.
Authors:
Cléverson O Silva; Erica Del Peloso Ribeiro; Antônio Wilson Sallum; Dimitris N Tatakis
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of periodontology     Volume:  81     ISSN:  1943-3670     ISO Abbreviation:  J. Periodontol.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-30     Completed Date:  2010-08-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  692-701     Citation Subset:  D; IM    
Affiliation:
Department of Prosthodontics and Periodontics, School of Dentistry at Piracicaba, University of Campinas, São Paulo, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adult
Dental Plaque Index
Epithelium / pathology
Female
Follow-Up Studies
Gingiva / pathology,  transplantation*
Gingival Hemorrhage / surgery
Gingival Recession / surgery
Graft Survival / physiology*
Humans
Keratins
Male
Palate / physiopathology,  surgery
Periodontal Attachment Loss / surgery
Periodontal Index
Periodontal Pocket / surgery
Postoperative Hemorrhage / classification
Prospective Studies
Smoking / physiopathology*
Surgical Flaps / pathology*,  physiology
Tissue and Organ Harvesting
Wound Healing / physiology
Chemical
Reg. No./Substance:
68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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