Document Detail

Free amino acid pools in some tissues of the pregnant rat.
MedLine Citation:
PMID:  3781479     Owner:  NLM     Status:  MEDLINE    
Plasma amino acid pools show important variations throughout the gestational period in the rat, with decreased values at mid-pregnancy and recovered levels before parturition. This decrease in amino acid levels at mid-pregnancy is mainly due to changes in the gluconeogenic amino acid group. During pregnancy, whole tissue amino acid pools increase in the liver but no changes appear in other studied tissues. However, individual gluconeogenic amino acid concentrations change significantly in skeletal muscle, skin and liver through the gestational period. Pregnancy may be understood as a challenge to the mother's metabolism but the pattern of tissue amino acid changes is not similar to that found in some stressant situations and it should be the net consequence of maternal adaptations to the increased metabolic needs.
M Pastor-Anglada; D López-Tejero; X Remesar
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme     Volume:  18     ISSN:  0018-5043     ISO Abbreviation:  Horm. Metab. Res.     Publication Date:  1986 Sep 
Date Detail:
Created Date:  1987-01-08     Completed Date:  1987-01-08     Revised Date:  2009-02-19    
Medline Journal Info:
Nlm Unique ID:  0177722     Medline TA:  Horm Metab Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  590-4     Citation Subset:  IM    
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MeSH Terms
Amino Acids / metabolism*
Kidney / metabolism
Liver / metabolism
Muscles / metabolism
Pregnancy, Animal / metabolism*
Rats, Inbred Strains
Skin / metabolism
Tissue Distribution
Reg. No./Substance:
0/Amino Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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