Document Detail

The Free Fall Machine--a ground-based facility for microgravity research in life sciences.
MedLine Citation:
PMID:  11539379     Owner:  NASA     Status:  MEDLINE    
A device is described in which a biological specimen is periodically accelerated for a short period. Each event is followed by a variable period of free fall. Assuming that the g-dose (expressed g s) has to surpass a certain minimal value to be perceived by cells, and in addition, there is a minimal time threshold for sensing a change in gravity, it is conceivable that conditions are created in which cells do not detect the periodic acceleration, and only experience the periodic free-fall movement as a long-term weightlessness condition. Using the cell-cycle progression of the unicellular green alga Chlamydomonas as an example, it is shown that with this device effects can be generated which are similar to those observed in satellite flights.
D A Mesland; A H Anton; H Willemsen; H van den Ende
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Microgravity science and technology     Volume:  9     ISSN:  0938-0108     ISO Abbreviation:  Microgravity Sci Technol     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1998-06-24     Completed Date:  1998-06-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  100971602     Medline TA:  Microgravity Sci Technol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  10-4     Citation Subset:  S    
European Space Research and Technology Center, Noordwijk, The Netherlands.
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MeSH Terms
Biological Science Disciplines / instrumentation*
Cell Cycle
Cell Division
Chlamydomonas / cytology*,  growth & development
Equipment Design
Evaluation Studies as Topic
Gravity, Altered
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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