Document Detail

Free air intraperitoneally during chemotherapy for acute lymphoblastic leukemia: consider pneumatosis cystoides intestinalis.
MedLine Citation:
PMID:  20147849     Owner:  NLM     Status:  MEDLINE    
Intraperitoneal free air in a child with acute lymphoblastic leukemia (ALL) treated with induction chemotherapy is an ominous sign suspective of gastrointestinal perforation. We report a case of pneumatosis cystoides intestinalis (PCI) with free intraperitoneal air without bowel perforation in a child with Down syndrome during ALL induction treatment. PCI is a physical sign characterized by gas-filled cysts of the submucosa or subserosa of the bowel that can lead to pneumoperitoneum. Clinical management of this case in respect to reported literature on PCI and specific characteristics of patients treated with ALL induction chemotherapy are discussed.
Ellis Groninger; Jan B F Hulscher; Bert Timmer; Rienk Y J Tamminga; Paul M A Broens
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  32     ISSN:  1536-3678     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-03-30     Revised Date:  2011-10-06    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-3     Citation Subset:  IM    
Department of Pediatric Oncology/Hematology of the Beatrix Children's Hospital, University of Groningen, The Netherlands.
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MeSH Terms
Child, Preschool
Pneumatosis Cystoides Intestinalis / etiology*,  psychology,  therapy
Pneumoperitoneum / etiology
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*

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