Document Detail


Frederick Akbar Mahomed.
MedLine Citation:
PMID:  1737655     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Frederick Akbar Mahomed was an Englishman of mixed Indian and Irish descent who made substantial contributions to the study of high blood pressure in a short professional life from 1872 to 1884. He was strongly influenced by the previous work of Richard Bright on kidney disease at his own hospital (Guy's Hospital in London) and by the contemporary pathological studies of Gull and Sutton on arteriolar changes in persons with high blood pressure. In detailed clinical studies, he separated chronic nephritis with secondary hypertension from what we now term essential hypertension. He described the constitutional basis and natural history of essential hypertension and pointed out that this disease could terminate with nephrosclerosis and renal failure. His clinical studies were done without the benefit of a sphygmomanometer but with the aid of a quantitative sphygmogram that he had initially developed while a medical student. He described characteristic features of the pressure pulse in patients with high blood pressure and in persons with arteriosclerosis consequent on aging. These pressure wave changes have recently been verified and explained. He contributed to a number of other advances in medical care, including blood transfusion and appendectomy for appendicitis. He initiated the Collective Investigation Record for the British Medical Association; this organization collected data from physicians practicing outside the hospital setting and was the precursor of modern collaborative clinical trials. Mahomed died from typhoid fever, almost certainly contracted from one of his patients, at age 35 at the height of his career.
Authors:
M F O'Rourke
Related Documents :
20471005 - Elevated neutrophil respiratory burst activity in essential hypertensive patients.
3038455 - Erythrocyte phosphoinositide metabolism in essential hypertensive patients and their no...
943425 - Norepinephrine infusion in normal subjects and patients with essential or renal hyperte...
6681025 - Adrenal and sympathetic nervous activity in subjects with "low' and "high' normal blood...
9321735 - The effects of environmental and lifestyle factors on blood pressure and the intermedia...
6487185 - Do any factors predict a favourable response to laser trabeculoplasty?
Publication Detail:
Type:  Biography; Historical Article; Journal Article; Portraits    
Journal Detail:
Title:  Hypertension     Volume:  19     ISSN:  0194-911X     ISO Abbreviation:  Hypertension     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-03-16     Completed Date:  1992-03-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7906255     Medline TA:  Hypertension     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  212-7     Citation Subset:  IM; Q    
Affiliation:
Medical Professorial Unit, St. Vincent's Hospital, Sydney, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Blood Pressure Determination / history
Cardiology / history
History, 20th Century
London
Personal Name Subject
Personal Name Subject:
F A Mahomed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genetic influences on the urinary excretion of aldosterone in children.
Next Document:  Personality, life events and coping in the oldest-old.