Document Detail

Framing postpartum hemorrhage as a consequence of human placental biology: an evolutionary and comparative perspective.
MedLine Citation:
PMID:  21909154     Owner:  HMD     Status:  MEDLINE    
Postpartum hemorrhage (PPH), the leading cause of maternal mortality worldwide, is responsible for 35 percent of maternal deaths. Proximately, PPH results from the failure of the placenta to separate from the uterine wall properly, most often because of impairment of uterine muscle contraction. Despite its prevalence and its well-described clinical manifestations, the ultimate causes of PPH are not known and have not been investigated through an evolutionary lens. We argue that vulnerability to PPH stems from the intensely invasive nature of human placentation. The human placenta causes uterine vessels to undergo transformation to provide the developing fetus with a high plane of maternal resources; the degree of this transformation in humans is extensive. We argue that the particularly invasive nature of the human placenta increases the possibility of increased blood loss at parturition. We review evidence suggesting PPH and other placental disorders represent an evolutionarily novel condition in hominins.
Elizabeth T Abrams; Julienne N Rutherford
Related Documents :
20121544 - Oxygen utilization in newborns at delivery.
17273434 - Research summaries for normal birth.
25380954 - Pregnancy in a patient with hepatic artery thrombosis after liver transplantation: a ca...
22482974 - Severe 2009 h1n1 infection in early pregnancy.
7190514 - Hormone patterns during bromocriptine-induced pregnancy in hyperprolactinemic patients.
17390284 - Corticosterone and foraging behavior in a pelagic seabird.
Publication Detail:
Type:  Historical Article; Journal Article    
Journal Detail:
Title:  American anthropologist     Volume:  113     ISSN:  0002-7294     ISO Abbreviation:  Am Anthropol     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-29     Completed Date:  2012-10-02     Revised Date:  2013-06-27    
Medline Journal Info:
Nlm Unique ID:  1275273     Medline TA:  Am Anthropol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  417-30     Citation Subset:  Q    
University of Illinois, Chicago.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biological Evolution
Embryo Implantation*
History, 20th Century
History, 21st Century
Maternal Mortality* / ethnology,  history
Postpartum Hemorrhage* / ethnology,  history
Women's Health / ethnology,  history
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Porocephalosis due to encysted Armillifer nymph presenting as an Acute Abdominal Emergency: Case Rep...
Next Document:  Diastolic Cardiac Pathology and Clinical Twin-Twin Transfusion Syndrome in Monochorionic/Diamniotic ...