| Fragrance Material Review on 2,2,5-Trimethyl-5-pentylcyclopentanone. | |
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MedLine Citation:
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PMID: 22425688 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A toxicologic and dermatologic review of 2,2,5-trimethyl-5-pentylcyclopentanone when used as a fragrance ingredient is presented. 2,2,5-trimethyl-5-pentylcyclopentanone is a member of the fragrance structural group Ketones Cyclopentanones and Cyclopentenones. The common characteristic structural element of the group members is a cyclopentanone or cyclopentenone ring with a straight or branched chain alkane or alkene substituent. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for 2,2,5-trimethyl-5-pentylcyclopentanone were evaluated then summarized and includes physical properties, acute toxicity, skin irritation, mucous membrane (eye) irritation, skin sensitization, and phototoxicity data. A safety assessment of the entire Ketones Cyclopentanones and Cyclopentenones will be published simultaneously with this document; please refer to Belsito et al., 2011(1) for an overall assessment of the safe use of this material and all Ketones Cyclopentanones and Cyclopentenones in fragrances. |
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Authors:
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J Scognamiglio; L Jones; C S Letizia; A M Api |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-14 |
Journal Detail:
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Title: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Volume: - ISSN: 1873-6351 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8207483 Medline TA: Food Chem Toxicol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Ltd. |
Affiliation:
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Research Institute for Fragrance Materials, Inc. 50 Tice Boulevard, Woodcliff Lake, NJ 07677, U.S.A. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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