Document Detail

Fragmentation hemolysis: an unusual indication for valve replacement in native valve infective endocarditis.
MedLine Citation:
PMID:  8701385     Owner:  NLM     Status:  MEDLINE    
Intravascular mechanical fragmentation of erythrocytes is an uncommon occurrence in native valve infective endocarditis. We report a case of fragmentation hemolysis in a patient with tricuspid valve endocarditis due to Staphylococcus aureus. She received transfusion of multiple units of packed red blood cells and ultimately required surgical removal of the affected valve to control the hemolytic process. We believe this to be only the fifth such reported case and the first in which surgical therapy was necessary to control the hemolytic process.
J D Gradon; M Hirschbein; J Milligan
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  89     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1996-09-05     Completed Date:  1996-09-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  818-20     Citation Subset:  AIM; IM    
Department of Medicine, Sinai Hospital, Baltimore, MD 21215, USA.
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MeSH Terms
Acute Disease
Anemia, Hemolytic / etiology*
Blood Transfusion
Endocarditis, Bacterial / complications*,  surgery
Heart Valve Prosthesis
Staphylococcal Infections / complications*,  surgery
Staphylococcus aureus*
Substance Abuse, Intravenous / complications
Tricuspid Valve*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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