| Fractional sodium excretion, urinary osmolality and specific gravity in preterm infants fed with fortified donor human milk. | |
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MedLine Citation:
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PMID: 16871349 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: This research was performed with the objective of investigating the renal effects on premature newborn infants of fortifying banked donor human milk. METHODS: Clinical intervention trial, of the before-and-after type, involving 28 premature newborn infants split into two groups by postconceptional age at the start of the study: GI < 34 weeks (n = 14) and GII >or= 34 weeks (n = 14), and assessed at three sample points: S1, on unfortified donor human milk, S2, after 3 days, and S3, after 10-13 days on fortified donor human milk. Nutrient intake, weight gain, fractional sodium excretion, urinary osmolality and specific density were compared with two-way ANOVA for repeated measures. RESULTS: Fluids, energy and sodium intakes were similar for both groups, and weight gain was satisfactory. Among the preterms with < 34 weeks postconceptional age, serum sodium was lower at the end of the study and the fractional sodium excretion was elevated at the start and at the end of the study (S1 = 2.11+/-1.05; S2 = 1.25+/-0.64; S3 = 1.62+/-0.88), with a significant difference in relation to GII (S1 = 1.34+/-0.94; S2 = 0.90+/-0.54; S3 = 0.91+/-0.82). Osmolality and urinary specific density were normal, with no differences between groups or collection dates. CONCLUSIONS: No adverse effects on the renal function of these preterms were detected as a result of being fed fortified donor human milk. |
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Authors:
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Atsuko Tanaka; Ligia M S S Rugolo; Antero F M Miranda; Cleide E P Trindade |
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Publication Detail:
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Type: Clinical Trial; Journal Article Date: 2006-07-21 |
Journal Detail:
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Title: Jornal de pediatria Volume: 82 ISSN: 0021-7557 ISO Abbreviation: J Pediatr (Rio J) Publication Date: 2006 Sep-Oct |
Date Detail:
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Created Date: 2006-10-09 Completed Date: 2007-02-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985188R Medline TA: J Pediatr (Rio J) Country: Brazil |
Other Details:
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Languages: eng Pagination: 335-40 Citation Subset: IM |
Affiliation:
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Departamento de Pediatria, Faculdade de Medicina de Marília, Marília, SP, Brasil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Analysis of Variance Calcium, Dietary / administration & dosage Food, Fortified* Gestational Age Humans Infant Infant Formula* Infant, Newborn Infant, Premature / metabolism* Infant, Very Low Birth Weight / metabolism* Milk, Human* Osmolar Concentration Phosphorus, Dietary / administration & dosage Sodium / blood, urine* Sodium, Dietary / administration & dosage* Specific Gravity Urine / chemistry Weight Gain |
| Chemical | |
Reg. No./Substance:
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0/Calcium, Dietary; 0/Phosphorus, Dietary; 0/Sodium, Dietary; 7440-23-5/Sodium |
| Comments/Corrections | |
Comment In:
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J Pediatr (Rio J). 2006 Sep-Oct;82(5):317-8
[PMID:
17028761
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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