Document Detail

Fractional filling with the microdepot technique as an alternative to bolus hyaluronic acid injections in facial volume restoration.
MedLine Citation:
PMID:  21605107     Owner:  NLM     Status:  In-Data-Review    
For volume restoration of the face, hyaluronic acid is conventionally injected through long, large-bore, 18-gauge needles because of the higher viscosity subtypes required. These hyaluronic acids are either more highly cross-linked or larger in particle size than the less-viscous subtypes. The microdepot injection technique involves using the 31-gauge BD insulin syringe (Becton-Dickinson, North Ryde, NSW Australia) to deposit small amounts of filler (0.05-0.1 mL) throughout the area of volume loss. The procedure is extremely well tolerated, requiring only topical and ice anaesthesia. Using this method, volume restoration can be achieved naturally and progressively over a period of time. Fractional filling every 3-4 months is continued until the desired level of volume correction is attained. Patients undergoing fractional filling followed over a 12-month period did not indicate any observable compromise in filler longevity, even when highly viscous hyaluronic acid fillers were injected through small-bore, 31-gauge insulin syringes.
Adrian C Lim; Patricia M Lowe
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Publication Detail:
Type:  Journal Article     Date:  2011-03-29
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  52     ISSN:  1440-0960     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  154-6     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists.
uRepublic Cosmetic Skin and Laser Clinic, Sydney Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
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