Document Detail

Fractal dimension in health and heart failure.
MedLine Citation:
PMID:  17061937     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Non-linear analysis of heart rate variability (HRV) can give additional information about autonomic control of the heart rate. This study applied the fractal dimension (FD) in a congestive heart failure (CHF) population. METHODS: FD and HRV were evaluated in a healthy population (n=21) and an end-stage heart failure population (n=21) using 1-h segments during the day and night from Holter recordings. RESULTS: CHF patients presented a loss of circadian variation in both FD and conventional time- and frequency-domain HRV indices. FD was higher in the CHF population both during the day and night. In the CHF population the correlation between FD and high-frequency power of HRV was lost. CONCLUSION: Day-night variations of heart rate fluctuations are lost in heart failure. Changes in FD reflecting physiological and pathophysiological changes were observed.
Frank Beckers; Bart Verheyden; Kurt Couckuyt; André E Aubert
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biomedizinische Technik. Biomedical engineering     Volume:  51     ISSN:  0013-5585     ISO Abbreviation:  Biomed Tech (Berl)     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-25     Completed Date:  2006-12-26     Revised Date:  2010-11-05    
Medline Journal Info:
Nlm Unique ID:  1262533     Medline TA:  Biomed Tech (Berl)     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  194-7     Citation Subset:  IM    
Laboratory of Experimental Cardiology, Department of Cardiovascular Diseases, University Hospital Gasthuisberg, Leuven, Belgium.
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MeSH Terms
Arrhythmias, Cardiac / diagnosis,  etiology,  physiopathology*
Biological Clocks*
Circadian Rhythm*
Diagnosis, Computer-Assisted / methods
Electrocardiography / methods*
Heart Failure / complications,  diagnosis,  physiopathology*
Heart Rate*
Middle Aged
Oscillometry / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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