Document Detail


Fourth-generation fluoroquinolones in the treatment of mycobacterial infectious keratitis after laser-assisted in situ keratomileusis surgery.
MedLine Citation:
PMID:  16391641     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Case report: Infectious keratitis after laser-assisted in situ keratomileusis (LASIK) is a rare complication that may be challenging to diagnose and treat. We discuss some of the reasons for difficulties diagnosing postoperative atypical or nontuberculous mycobacterial infection and establishing an effective treatment, with reference to reports of comparative antibacterial activity of the most commonly used antibiotics.Comments: To the best of our knowledge, we are the first to report the use of the fourth-generation fluoroquinolone moxifloxacin in combination therapy for the successful treatment of this condition.
Authors:
Sao Bing Lee; Karine M Oliver; Yi Ning J Strube; Subhash K Mohan; Allan R Slomovic
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  40     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2006-01-04     Completed Date:  2006-03-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  750-3     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology and Vision Science, University of Toronto, Ontario.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / therapeutic use*
Aza Compounds / therapeutic use*
Clarithromycin / therapeutic use
Corneal Ulcer / drug therapy*,  microbiology
Drug Therapy, Combination
Eye Infections, Bacterial / drug therapy*
Female
Humans
Keratomileusis, Laser In Situ*
Microbial Sensitivity Tests
Middle Aged
Mycobacteria, Atypical / drug effects,  isolation & purification
Mycobacterium Infections, Atypical / drug therapy*
Postoperative Complications*
Quinolines / therapeutic use*
Surgical Flaps
Tobramycin / therapeutic use
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Aza Compounds; 0/Quinolines; 0/moxifloxacin; 32986-56-4/Tobramycin; 81103-11-9/Clarithromycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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