Document Detail

Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia: Recommendations for family physicians.
MedLine Citation:
PMID:  24829003     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To revise diagnostic strategies for Alzheimer disease (AD), update recommendations on symptomatic treatment of dementia, and provide an approach to rapidly progressive and early-onset dementias.
COMPOSITION OF THE COMMITTEE: Experts and delegates representing relevant disciplines from diverse regions across Canada discussed and agreed upon revisions to the 2006 guidelines.
METHODS: The GRADE (grading of recommendations, assessment, development, and evaluation) system was used to evaluate consensus on recommendations, which was defined as when 80% or more of participants voted for the recommendation. Evidence grades are reported where possible.
REPORT: Important for FPs, despite advances in liquid biomarkers and neuroimaging, the diagnosis of dementia in Canada remains fundamentally clinical. New core clinical criteria for the diagnosis of AD now recognize less common, nonamnestic forms. Early-onset dementia, a rare but important condition, should prompt referral to specialists with access to genetic counselors. Rapidly progressive dementia, poorly defined in the literature, is described to facilitate detection of this rare but important condition. There are new expanded indications for cholinesterase inhibitors beyond AD, as well as guidelines for their discontinuation, which had not been previously described. New evidence regarding use of memantine, antidepressants, and other psychotropic medications in dementia care is presented.
CONCLUSION: Several recommendations from the Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia are relevant to FPs. For guidelines to remain useful, family physicians should participate in all stages of the ongoing development process, including topic selection.
Ainsley Moore; Christopher Patterson; Linda Lee; Isabelle Vedel; Howard Bergman
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Publication Detail:
Type:  REVIEW    
Journal Detail:
Title:  Canadian family physician Medecin de famille canadien     Volume:  60     ISSN:  1715-5258     ISO Abbreviation:  Can Fam Physician     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0120300     Medline TA:  Can Fam Physician     Country:  -    
Other Details:
Languages:  ENG     Pagination:  433-438     Citation Subset:  -    
Copyright Information:
Copyright© the College of Family Physicians of Canada.
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