Document Detail

Fourier analysis of circadian blood pressure profile in secondary hypertension.
MedLine Citation:
PMID:  9205936     Owner:  NLM     Status:  MEDLINE    
Different types of statistical methods have been used for circadian blood pressure (BP) rhythm analysis in secondary forms of hypertension. In the present study, we used the two-step statistical approach by Fourier analysis with four harmonics for the parametrization of the diurnal BP pattern in secondary hypertension. In 43 essential hypertensives (EH), eight patients with aldosterone producing adenoma (APA), 25 with idiopathic hyperaldosteronism (IHA), four with glucocorticoid remediable hyperaldosteronism (GRH) and seven with renovascular hypertension (RVH), 24-h ambulatory BP was measured. The diurnal BP and heart rate (HR) rhythm was present in more than 70% of patients with secondary hypertension, without significant differences with EH and despite the attenuation in the degree of the nocturnal BP fall. In conclusion, the statement that secondary hypertension is characterized by an abnormal diurnal rhythm of BP is a gross over-simplification. Our findings suggest that the two-step method with four harmonics Fourier analysis may represent a useful method and a more complete statistical approach to providing circadian parametrization of the 24-h profile in secondary hypertension.
F Rabbia; F Veglio; G Martini; M P Sibona; P Molino; C Zocchi; L Chiandussi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of human hypertension     Volume:  11     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-08-20     Completed Date:  1997-08-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  IM    
Department of Medicine and Experimental Oncology, S. Vito Hospital, University of Turin, Italy.
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MeSH Terms
Blood Pressure*
Circadian Rhythm
Fourier Analysis
Hyperaldosteronism / physiopathology*
Hypertension, Renovascular / physiopathology*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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