| Four successful pregnancies in a patient with mucopolysaccharidosis type I treated by allogeneic bone marrow transplantation. | |
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MedLine Citation:
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PMID: 19280364 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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To date, little is known about the fertility of women suffering from mucopolysaccharidosis type I (MPS I). We report on a female patient with MPS I treated by allogeneic bone marrow transplantation (BMT) at the age of 4 years (after a conditioning regimen containing busulfan 16 mg/kg and cyclophosphamide 100 mg/kg) who had four successful pregnancies without any reproductive assistance. Clinical and biological examinations of the children were normal. On the basis of this case, we discuss the fertility counselling of female MPS I patients at the time of BMT. |
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Authors:
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G Remérand; E Merlin; R Froissart; F Brugnon; J Kanold; L Janny; F Deméocq |
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Publication Detail:
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Type: Journal Article Date: 2009-03-13 |
Journal Detail:
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Title: Journal of inherited metabolic disease Volume: 32 Suppl 1 ISSN: 1573-2665 ISO Abbreviation: J. Inherit. Metab. Dis. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2012-12-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7910918 Medline TA: J Inherit Metab Dis Country: Netherlands |
Other Details:
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Languages: eng Pagination: 111-3 Citation Subset: IM |
Affiliation:
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CHU Clermont-Ferrand, Centre Régional de Cancérologie et Thérapie Cellulaire Pédiatrique, Clermont-Ferrand, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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