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Four-dimensional phase contrast MRI with accelerated dual velocity encoding.
MedLine Citation:
PMID:  22282344     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To validate a novel approach for accelerated four-dimensional phase contrast MR imaging (4D PC-MRI) with an extended range of velocity sensitivity. MATERIALS AND METHODS: 4D PC-MRI data were acquired with a radially undersampled trajectory (PC-VIPR). A dual V(enc) (dV(enc) ) processing algorithm was implemented to investigate the potential for scan time savings while providing an improved velocity-to-noise ratio. Flow and velocity measurements were compared with a flow pump, conventional 2D PC MR, and single V(enc) 4D PC-MRI in the chest of 10 volunteers. RESULTS: Phantom measurements showed excellent agreement between accelerated dV(enc) 4D PC-MRI and the pump flow rate (R(2) ≥ 0.97) with a three-fold increase in measured velocity-to-noise ratio (VNR) and a 5% increase in scan time. In volunteers, reasonable agreement was found when combining 100% of data acquired with V(enc) = 80 cm/s and 25% of the high V(enc) data, providing the VNR of a 80 cm/s acquisition with a wider velocity range of 160 cm/s at the expense of a 25% longer scan. CONCLUSION: Accelerated dual V(enc) 4D PC-MRI was demonstrated in vitro and in vivo. This acquisition scheme is well suited for vascular territories with wide ranges of flow velocities such as congenital heart disease, the hepatic vasculature, and others. J. Magn. Reson. Imaging 2012;. © 2012 Wiley Periodicals, Inc.
Authors:
Elizabeth J Nett; Kevin M Johnson; Alex Frydrychowicz; Alejandro Munoz Del Rio; Eric Schrauben; Christopher J Francois; Oliver Wieben
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-26
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  -     ISSN:  1522-2586     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Affiliation:
Department of Medical Physics, University of Wisconsin, Madison, Wisconsin, USA. janus@wisc.edu.
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