Document Detail

Four cases of a secondary Cushingoid state following local triamcinolone acetonide (Kenacort) injection.
MedLine Citation:
PMID:  12164373     Owner:  NLM     Status:  MEDLINE    
Intra-articular, paratendinous or other soft tissue corticosteroid injections are well-recognised treatment modalities for rheumatic conditions in which a debilitating inflammatory component persists. A corticosteroid injection that is locally administered only sporadically evokes adverse effects. We report four cases of secondary Cushingoid state, twice due to single, and twice due to repetitive triamcinolone acetonide (TCA: Kenacort) injection. A consulted general practitioner, internist and gynaecologist were not aware of the possibility that such a local injection may evoke a Cushingoid state with moon face, buffalo hump and/or disturbance of the menstrual cycle. Therefore we describe here the four cases we recently encountered.
T L Th A Jansen; E N Van Roon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Netherlands journal of medicine     Volume:  60     ISSN:  0300-2977     ISO Abbreviation:  Neth J Med     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-08-07     Completed Date:  2002-08-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0356133     Medline TA:  Neth J Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  151-3     Citation Subset:  IM    
Medical Centre Leeuwarden, Department of Rheumatology, The Netherlands. T.JANSEN@ZNB.NL
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MeSH Terms
Cushing Syndrome / chemically induced*
Glucocorticoids / administration & dosage,  adverse effects*
Injections, Intra-Articular
Middle Aged
Triamcinolone Acetonide / administration & dosage,  adverse effects*
Reg. No./Substance:
0/Glucocorticoids; 76-25-5/Triamcinolone Acetonide
Comment In:
Neth J Med. 2002 Apr;60(3):130-2   [PMID:  12164369 ]

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