Document Detail

A Four-Criterion Selection Procedure for Atherosclerotic Plaque Elasticity Reconstruction Based on in Vivo Coronary Intravascular Ultrasound Radial Strain Sequences.
MedLine Citation:
PMID:  23196202     Owner:  NLM     Status:  In-Data-Review    
Plaque elasticity (i.e., modulogram) and morphology are good predictors of plaque vulnerability. Recently, our group developed an intravascular ultrasound (IVUS) elasticity reconstruction method which was successfully implemented in vitro using vessel phantoms. In vivo IVUS modulography, however, remains a major challenge as the motion of the heart prevents accurate strain field estimation. We therefore designed a technique to extract accurate strain fields and modulograms from recorded IVUS sequences. We identified a set of four criteria based on tissue overlapping, RF-correlation coefficient between two successive frames, performance of the elasticity reconstruction method to recover the measured radial strain, and reproducibility of the computed modulograms over the cardiac cycle. This four-criterion selection procedure (4-CSP) was successfully tested on IVUS sequences obtained in twelve patients referred for a directional coronary atherectomy intervention. This study demonstrates the potential of the IVUS modulography technique based on the proposed 4-CSP to detect vulnerable plaques in vivo.
Simon Le Floc'h; Guy Cloutier; Yoshifumi Saijo; Gérard Finet; Saami K Yazdani; Flavien Deleaval; Gilles Rioufol; Roderic I Pettigrew; Jacques Ohayon
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  38     ISSN:  1879-291X     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  2084-97     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
Laboratory TIMC-IMAG/DyCTiM, UJF, CNRS UMR 5525, Grenoble, France.
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