Document Detail

Fortified human milk in the small for gestational age neonate.
MedLine Citation:
PMID:  17901665     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the nutritional advantage of fortified human milk in the small for gestational age neonate. METHODS: Term asymmetric small for gestational age babies were randomly assigned to either the study group or the control group. The babies in the study group received fortified EBM, (more proteins, calories, vitamins and minerals) whereas babies in the control group received EBM only. Babies were followed up weekly for a period of 28 +/- 2 days for physical growth (weight, length and OFC). Biochemical markers of nutritional status (Blood urea, serum calcium, phosphorus, alkaline phosphatase, serum electrolytes and serum protein) were done initially and then on Day 28 +/- 2. RESULTS: The weight gain in the study group (38.77 +/- 7.43 g/day) was significantly better than in the control group (28.71 +/- 3.18 g/day). The length and OFC gain in the study group (1.14 +/- 0.33 cm/week and 0.62 +/- 0.07 cms/week, respectively) were significantly better than in the control group (0.87 +/- 0.17 cm/week and 0.49 +/- 0.07 cm/week respectively). The biochemical markers of nutrition, however, were not significantly different in the two groups. CONCLUSION: Fortified breast milk results in improved physical growth in the term asymmetric small for gestational age neonate.
Geeta Gathwala; Meenu Chawla; Veena Singh Gehlaut
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  74     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-28     Completed Date:  2007-11-08     Revised Date:  2009-07-15    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  815-8     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, Pt. B.D.S Post-Graduate Institute of Medical Sciences, Rohtak, India.
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MeSH Terms
Biological Markers / analysis
Food, Fortified*
Infant Formula*
Infant Nutritional Physiological Phenomena
Infant, Newborn
Infant, Small for Gestational Age / physiology*
Milk, Human*
Weight Gain*
Reg. No./Substance:
0/Biological Markers
Comment In:
Indian J Pediatr. 2008 Nov;75(11):1183-4; author reply 1184-5   [PMID:  18818889 ]

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