Document Detail


Formerly unclassified, acid-stable equine picornaviruses are a third equine rhinitis B virus serotype in the genus Erbovirus.
MedLine Citation:
PMID:  16963761     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acid-stable equine picornaviruses (ASPs) were identified as a distinct serotype of equine picornaviruses that were isolated from nasal swabs taken from horses with acute febrile respiratory disease in the UK and Japan, and were placed in the group of unclassified picornaviruses. The nucleotide sequence of the P1 region, encoding the capsid proteins, was determined for three ASP isolates from the UK and the sequences were aligned with published sequences of Equine rhinitis B virus (ERBV), genus Erbovirus, including acid-labile ERBV1 and ERBV2 and the recently identified acid-stable ERBV1. The ASPs belong to the same phylogenetic group, composed of five acid-stable ERBV1 isolates. ERBV1 rabbit antiserum neutralized the ASP isolates at approximately 1/10 titre relative to acid-stable and acid-labile ERBV1 isolates, supporting prior findings that ASPs are a distinct serotype, albeit cross-neutralizing weakly with ERBV1. The genus Erbovirus therefore presently comprises three serotypes: ERBV1, ERBV2 and the proposed ERBV3.
Authors:
Wesley D Black; Michael J Studdert
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of general virology     Volume:  87     ISSN:  0022-1317     ISO Abbreviation:  J. Gen. Virol.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-11     Completed Date:  2006-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0077340     Medline TA:  J Gen Virol     Country:  England    
Other Details:
Languages:  eng     Pagination:  3023-7     Citation Subset:  IM    
Affiliation:
Centre for Equine Virology, School of Veterinary Science, The University of Melbourne, Parkville, VIC 3010, Australia.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/DQ108383;  DQ108384;  DQ108385
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MeSH Terms
Descriptor/Qualifier:
Acids
Amino Acid Sequence
Animals
Horses / virology*
Hydrogen-Ion Concentration
Molecular Sequence Data
Phylogeny
Picornaviridae / classification*,  genetics
Rhinitis / veterinary,  virology
Serotyping
Viral Structural Proteins / chemistry,  genetics
Chemical
Reg. No./Substance:
0/Acids; 0/Viral Structural Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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