| Formation of multicellular aggregates under different conditions of microenvironment. | |
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MedLine Citation:
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PMID: 20201409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multicellular aggregates (spheroids) represent an intermittent level between monolayer growing cells and tissue culture. Spheroids are rather objective model of the three-dimensional growth and organization, the cell-to-cell interactions and influence of microenvironmental conditions on tumour microaggregates. In our work formation and growth of spheroids depends on concentration of CMC and FCS. Conditions of microenvironment influence on intensiveness of proliferation as well as on cells adhesiveness and formation of microaggregates. |
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Authors:
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L Garmanchouk; O Perepelytsina; M Sydorenko; L I Ostapchenko |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: T?Sitologii?a i genetika Volume: 44 ISSN: 0564-3783 ISO Abbreviation: Tsitol. Genet. Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-03-05 Completed Date: 2010-05-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0101671 Medline TA: Tsitol Genet Country: Ukraine |
Other Details:
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Languages: eng Pagination: 25-9 Citation Subset: IM |
Affiliation:
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Department of Biotechnical Problems of Diagnostics, Institute problems of Cryobiology and Criomedicine NAN, Ukraine, Kyiv. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carboxymethylcellulose / chemistry Cattle Cell Adhesion / physiology Cell Culture Techniques / methods Cell Line, Tumor Cell Proliferation Culture Media / chemistry Fetal Blood / chemistry Humans Models, Biological* Serum / chemistry Spheroids, Cellular / cytology*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Culture Media; 9004-32-4/Carboxymethylcellulose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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