Document Detail

Formalin instillation for uncontrolled radiation induced haemorrhagic proctitis.
MedLine Citation:
PMID:  21568145     Owner:  NLM     Status:  In-Process    
BACKGROUND: Radiation induced haemorrhagic proctitis is a well recognized complication of pelvic radiotherapy and its treatment is quite challenging.
AIM: To evaluate the efficacy of local instillation of 4% formalin in the management of uncontrolled radiation induced haemorrhagic proctitis.
METHODS: This prospective study included twenty-three patients who underwent formalin instillation. We documented the control of the symptoms, assessed the outcome of the treatment, presence of complications & long term results.
RESULTS: All patients were followed for a median of 13 months. In 15 patients, the bleeding stopped after a single treatment and in 6 after a second session. Only two patients required formalin instillation for the third time. During the follow-up period all patients were reviewed systemically with reference to the pretreatment complaints. No recurrent rectal bleeding occurred, bowel frequency was decreased and no further blood transfusion was required.
CONCLUSION: Local instillation of 4% formalin is an effective treatment for uncontrolled radiation induced haemorrhagic proctitis.
Gautam Chattopadhyay; Dipankar Ray; Saurav Chakravartty; Subhayan Mandal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tropical gastroenterology : official journal of the Digestive Diseases Foundation     Volume:  31     ISSN:  0250-636X     ISO Abbreviation:  Trop Gastroenterol     Publication Date:    2010 Oct-Dec
Date Detail:
Created Date:  2011-05-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8107122     Medline TA:  Trop Gastroenterol     Country:  India    
Other Details:
Languages:  eng     Pagination:  291-4     Citation Subset:  IM    
Department of Surgical Gastroenterology, Medical College, Kolkata, India.
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