Document Detail

Formaldehyde concentrations in household air of asthma patients determined using colorimetric detector tubes.
MedLine Citation:
PMID:  23278296     Owner:  NLM     Status:  MEDLINE    
Formaldehyde is a colorless, pungent gas commonly found in homes and is a respiratory irritant, sensitizer, carcinogen, and asthma trigger. Typical household sources include plywood and particleboard, cleaners, cosmetics, pesticides, and others. Development of a fast and simple measurement technique could facilitate continued research on this important chemical. The goal of this research is to apply an inexpensive short-term measurement method to find correlations between formaldehyde sources and concentration, and formaldehyde concentration and asthma control. Formaldehyde was measured using 30-min grab samples in length-of-stain detector tubes in homes (n = 70) of asthmatics in the Boston, MA area. Clinical status and potential formaldehyde sources were determined. The geometric mean formaldehyde level was 35.1 ppb and ranged from 5 to 132 ppb. Based on one-way ANOVA, t-tests, and linear regression, predictors of log-transformed formaldehyde concentration included absolute humidity, season, and the presence of decorative laminates, fiberglass, or permanent press fabrics (P < 0.05), as well as temperature and household cleaner use (P < 0.10). The geometric mean formaldehyde concentration was 57% higher in homes of children with very poorly controlled asthma compared to homes of other asthmatic children (P = 0.078). This study provides a simple method for measuring household formaldehyde and suggests that exposure is related to poorly controlled asthma.
K C Dannemiller; J S Murphy; S L Dixon; K G Pennell; E M Suuberg; D E Jacobs; M Sandel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2013-01-31
Journal Detail:
Title:  Indoor air     Volume:  23     ISSN:  1600-0668     ISO Abbreviation:  Indoor Air     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-07-11     Completed Date:  2014-04-22     Revised Date:  2014-08-05    
Medline Journal Info:
Nlm Unique ID:  9423515     Medline TA:  Indoor Air     Country:  England    
Other Details:
Languages:  eng     Pagination:  285-94     Citation Subset:  IM    
Copyright Information:
© 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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MeSH Terms
Air / analysis
Asthma / epidemiology*
Boston / epidemiology
Child, Preschool
Environmental Monitoring / methods*
Formaldehyde / analysis*
Middle Aged
Regression Analysis
Young Adult
Grant Support
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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