Document Detail


Forever young.
MedLine Citation:
PMID:  20141830     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Propagation of a species requires periodic cell renewal to avoid clonal senescence. Liu et al. (2010) now describe a new mechanism of cell renewal in budding yeast, in which damaged protein aggregates are transported out of the daughter buds along actin cables to preserve youthfulness.
Authors:
Leonard Guarente
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell     Volume:  140     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-02-09     Completed Date:  2010-02-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  176-8     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Paul F. Glenn Lab, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. leng@mit.edu
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MeSH Terms
Descriptor/Qualifier:
Actins / metabolism
Protein Transport
Saccharomyces cerevisiae / cytology*,   metabolism
Saccharomyces cerevisiae Proteins / metabolism
Chemical
Reg. No./Substance:
0/Actins; 0/Saccharomyces cerevisiae Proteins
Comments/Corrections
Comment On:
Cell. 2010 Jan 22;140(2):257-67   [PMID:  20141839]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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