Document Detail


Forensic Analysis of mtDNA Haplotypes from Two Rural Communities in Haiti Reflects Their Population History.
MedLine Citation:
PMID:  22583388     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
  Very little genetic data exist on Haitians, an estimated 1.2 million of whom, not including illegal immigrants, reside in the United States. The absence of genetic data on a population of this size reduces the discriminatory power of criminal and missing-person DNA databases in the United States and Caribbean. We present a forensic population study that provides the first genetic data set for Haiti. This study uses hypervariable segment one (HVS-1) mitochondrial DNA (mtDNA) nucleotide sequences from 291 subjects primarily from rural areas of northern and southern Haiti, where admixture would be minimal. Our results showed that the African maternal genetic component of Haitians had slightly higher West-Central African admixture than African-Americans and Dominicans, but considerably less than Afro-Brazilians. These results lay the foundation for further forensic genetics studies in the Haitian population and serve as a model for forensic mtDNA identification of individuals in other isolated or rural communities.
Authors:
Jamie L Wilson; Vertus Saint-Louis; Jensen O Auguste; Bruce A Jackson
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-14
Journal Detail:
Title:  Journal of forensic sciences     Volume:  -     ISSN:  1556-4029     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 American Academy of Forensic Sciences.
Affiliation:
Biomedical Engineering and Biotechnology Program, University of Massachusetts, Lowell, MA 01854 Biotechnology and Forensic DNA Science Program, Massachusetts Bay Community College, Wellesley Hills, MA 02481 École Normale Supérieure, University of Haiti, Port-au-Prince, Haiti.
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