Document Detail

Foreign body granulomas after injection of Bio-alcamid for lip augmentation.
MedLine Citation:
PMID:  19720259     Owner:  NLM     Status:  MEDLINE    
Bio-alcamid is one of the newest agents on the market for soft tissue augmentation. Seven studies were documented in the medical literature that examined the safety of Bio-alcamid (Polymekon, Brindisy, Italy); all reported no cases of tissue migration, foreign body granulomas, allergenicity, or interference with the control of cell proliferation. On 2 separate occasions, a woman who had recently undergone lip augmentation presented at our hospital with submucosal nodules of the lip. Histologic examination revealed multiple foreign body-type granulomas composed of giant cells, epithelioid cells, and chronic inflammation of the lip. Efforts to produce a cosmetic material that fulfills all the criteria as an "ideal" agent has not yet been found because all injectable foreign agents have the potential to induce adverse reactions. Caution must be exercised in all cases and the risks explained to the patient before its use.
Sharon Akrish; Dan Dayan; Shlomo Taicher; Iris Adam; Rafael M Nagler
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-03-06
Journal Detail:
Title:  American journal of otolaryngology     Volume:  30     ISSN:  1532-818X     ISO Abbreviation:  Am J Otolaryngol     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-09-01     Completed Date:  2009-10-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000029     Medline TA:  Am J Otolaryngol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  356-9     Citation Subset:  IM    
Department Oral Pathology and Medicine, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.
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MeSH Terms
Acrylic Resins
Biocompatible Materials / adverse effects*
Cosmetic Techniques / adverse effects*
Granuloma, Foreign-Body / chemically induced*,  etiology,  surgery
Injections, Subcutaneous / adverse effects
Lip / surgery*
Postoperative Complications / chemically induced,  etiology,  surgery
Treatment Outcome
Reg. No./Substance:
0/Acrylic Resins; 0/Bio-Alcamid; 0/Biocompatible Materials

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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