Document Detail


Forearm reactive hyperemic blood flow and arm-cranking exercise capacity in healthy and heart failure subjects.
MedLine Citation:
PMID:  12140808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The relationship between lower limbs maximal vasodilatory capacity and exercise capacity in congestive heart failure (CHF) and healthy subjects has been well-documented. However, the relationship between upper limbs maximal vasodilatory capacity and exercise is less well-established. METHODS AND RESULTS: Twelve patients with CHF, 16 age-matched normal subjects, and 11 very fit individuals underwent an arm-cranking exercise test using maximal oxygen uptake (arm VO(2max)) and measurements of peak forearm reactive hyperemic blood flow. Despite similar forearm strength, arm VO(2max) was significantly reduced in patients with CHF when compared to normal and very fit individuals (13.9 +/- 2.9, 23.5 +/- 4.8, and 36.4 +/- 8.5 mL/kg/min, respectively, P <.05). Similarly, peak reactive hyperemia was lower in CHF patients as compared to normal and very fit individuals (18.6 +/- 5.9, 24.3 +/- 5.8, and 41.1 +/- 8.1 mL/100 mL/min, respectively, P <.05). There was a strong relationship between peak reactive hyperemic blood flow and arm VO(2max) (r =.75; P <.001) in all subjects. CONCLUSIONS: These results suggest a significant relationship between forearm vasodilatory capacity and arm-cranking VO(2max) in CHF patients, sedentary, and very fit individuals.
Authors:
Lizanne M Bussières; Martin Juneau; Julie Lalongé; Michel White; Jean-Lucien Rouleau
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of cardiac failure     Volume:  8     ISSN:  1071-9164     ISO Abbreviation:  J. Card. Fail.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-07-25     Completed Date:  2002-11-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9442138     Medline TA:  J Card Fail     Country:  United States    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
Affiliation:
Department of Medicine, Montreal Heart Institute, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Flow Velocity / physiology
Exercise
Exercise Tolerance*
Female
Forearm / blood supply*
Heart Failure / complications,  physiopathology*
Humans
Male
Middle Aged
Oxygen Consumption / physiology*
Reference Values
Vasodilation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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