Document Detail

Forearm bone density and grip strength in women after menopause, with and without estrogen replacement therapy.
MedLine Citation:
PMID:  7731385     Owner:  NLM     Status:  MEDLINE    
Peaking in young adulthood, both bone mass and muscle strength decrease with ageing, but bone loss may accelerate after the menopause and can be delayed by estrogen replacement therapy (ERT). This study was designed to evaluate whether, like bone density, the muscle strength was affected by the onset of menopause and/or ERT. First grip strength (GS) of young female adults (group III; n = 18; age (+/- S.E.M.) 21.8 +/- 0.4 years) was compared to that of postmenopausal women, who were divided into two groups. Group I (n = 22; age 59.6 +/- 1.6 years) was 12.5 +/- 1.7 years after the menopause and received no ERT, and group II (n = 21; age 59.5 +/- 1.1 years) was 8.3 +/- 1.2 years after the menopause and had received ERT for 3.9 +/- 2.3 years at the time of the study. GS of the postmenopausal women was significantly (P < 0.005) lower than that of the young female adults. GS did not differ significantly between both postmenopausal groups. Further analysis revealed a weak negative correlation of years since menopause with forearm bone density (r = -0.37, P < or = 0.023 for group II and III together), but not with GS. It is concluded that the later onset of menopause and estrogen replacement therapy do not seem to have a noticeable influence on muscle strength.
E Preisinger; Y Alacamlioglu; T Saradeth; K L Resch; G Holzer; M Metka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Maturitas     Volume:  21     ISSN:  0378-5122     ISO Abbreviation:  Maturitas     Publication Date:  1995 Jan 
Date Detail:
Created Date:  1995-06-01     Completed Date:  1995-06-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7807333     Medline TA:  Maturitas     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  57-63     Citation Subset:  IM; S    
Department of Physical Medicine and Rehabilitation, Medical School (AKH), University of Vienna, Austria.
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MeSH Terms
Age Factors
Bone Density / physiology*
Estrogen Replacement Therapy*
Hand Strength / physiology*
Middle Aged
Postmenopause / physiology*

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