Document Detail

Foot problems in patients with diabetes and chronic kidney disease.
MedLine Citation:
PMID:  22348369     Owner:  NLM     Status:  In-Data-Review    
There is a much higher incidence of diabetic foot disease in those with concurrent renal disease and outcomes, including amputation and mortality, are generally poorer. The risk factors contributing to the higher incidence of foot disease in those with both diabetes and renal disease are outlined, and the evidence explored demonstrating higher incidence of foot disease across categories of renal disease, including impaired renal function (chronic kidney disease stages 3 and 4), haemodialysis, continuous ambulatory peritoneal dialysis, renal transplantation and simultaneous pancreas and kidney transplantation. Three major pathological aspects of diabetic foot disease in which concurrent renal disease either contributes to a higher incidence, or modifies the clinical manifestations and outcomes, are described: ulceration; Charcot neuroarthropathy and necrotic toes. Pathophysiology, clinical features and management strategies for these three conditions are described. Finally, the evidence for preventative strategies for foot disease is explored, and the important role of speed of access to specialist multi-disciplinary diabetic foot services discussed.
Jonathan Valabhji
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of renal care     Volume:  38 Suppl 1     ISSN:  1755-6686     ISO Abbreviation:  J Ren Care     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-02-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101392167     Medline TA:  J Ren Care     Country:  France    
Other Details:
Languages:  eng     Pagination:  99-108     Citation Subset:  N    
Copyright Information:
© 2012 European Dialysis and Transplant Nurses Association/European Renal Care Association.
Department of Diabetes and Endocrinology, Imperial College Healthcare NHS Trust and Division of Medicine, Imperial College London, UK.
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