Document Detail

Food and water restriction protocols: physiological and behavioral considerations.
MedLine Citation:
PMID:  11487246     Owner:  NLM     Status:  MEDLINE    
Food and water restriction protocols are common in animal research, yet they often elicit discussion and controversy among institutional animal care and use committee members who review them. Determining a single standard by which all restriction protocols can be evaluated or performed may not be realistic. However, information about the physiologic and behavioral impact of food and water restriction can provide a basis for making rational judgments about these issues in general. This review will discuss the physiologic and behavioral consequences of food or water deprivation periods of 24 h or less and of chronic restriction schedules, with special reference to protocols that use food or water restriction as a motivational tool for behavioral training.
L A Toth; T W Gardiner
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Contemporary topics in laboratory animal science / American Association for Laboratory Animal Science     Volume:  39     ISSN:  1060-0558     ISO Abbreviation:  Contemp Top Lab Anim Sci     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-08-06     Completed Date:  2001-08-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9204153     Medline TA:  Contemp Top Lab Anim Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9-17     Citation Subset:  IM    
Animal Resources Center, St. Jude Childrens Research Hospital, Memphis, TN 38105, USA.
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MeSH Terms
Animal Welfare*
Animals, Laboratory*
Behavior, Animal
Food Deprivation / physiology*
Research Design
Water Deprivation / physiology*
Grant Support

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