Document Detail

Food sensitivity in reflux esophagitis.
MedLine Citation:
PMID:  27414     Owner:  NLM     Status:  MEDLINE    
We examined 66 patients with pain of possible esophageal origin for sensitivity to intraesophageal infusions of coffee, orange juice, spicy tomato drink, or HCl of varying concentrations as an addendum to their acid infusion (Bernstein) tests. Compared to Berstein-negative subjects, acid-sensitive patients were sensitive to infusion of coffee (P less than 0.01), orange juice (P less than 0.001), and tomato drink (P less than 0.001). Patients were largely insensitive to HCl solutions with a titratable acidity of 1 mEq per liter or less, less than the least acidic food solution tested. However, Berstein-positive patients were still highly sensitive to infusions of coffee, orange juice, and tomato drink adjusted to pH 7 (P less than 0.001). Patients were unable to differentiate symptoms caused by acid or food infusions, and solutions did not differ in the duration of infusion needed either to cause symptoms or to relieve them by saline. We conclude that the pain of esophagitis is nonspecific and can be precipitated by variety of seemingly unrelated substances.
S F Price; K W Smithson; D O Castell
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Gastroenterology     Volume:  75     ISSN:  0016-5085     ISO Abbreviation:  Gastroenterology     Publication Date:  1978 Aug 
Date Detail:
Created Date:  1978-09-15     Completed Date:  1978-09-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0374630     Medline TA:  Gastroenterology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  240-3     Citation Subset:  AIM; IM    
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MeSH Terms
Coffee / adverse effects
Esophagitis, Peptic / complications,  diagnosis*,  etiology
Food / adverse effects*
Fruit / adverse effects
Heartburn / etiology*
Hydrogen-Ion Concentration
Middle Aged
Vegetables / adverse effects
Reg. No./Substance:

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