Document Detail

Food polyamine and cardiovascular disease -an epidemiological study-.
MedLine Citation:
PMID:  23121753     Owner:  NLM     Status:  In-Data-Review    
The purpose of this study was to examine the contribution of dietary polyamines toward preventing cardiovascular disease (CVD). Age-standardized mortality rates as well as other relevant information regarding individuals with CVD were gathered from the World Health Organization and the International Monetary Fund in 48 different European and other Western countries. Food supply data were collected from the database of the United Nations, and the amount of dietary polyamines was estimated by using polyamine concentrations in foods from published sources. The association between CVD mortality and the amount of polyamines was investigated by performing a series of multiple linear regression analyses. Analyses using factors known to modulate the risk of CVD including: Gross Domestic Product (GDP) (standardized regression coefficient (r) = -0.786, p < 0.001) and the amount of fruits, vegetable, nuts, and beans (r = -0.183, p = 0.001) but not including polyamines, showed negative associations with CVD, while smoking rate (r = 0.139, p = 0.041) and whole milk amount (r = 0.131, p = 0.028) showed positive associations with CVD. When the amount of polyamines was added to the analyses as a covariate, GDP (r = -0.864, p < 0.001) and polyamines (r = -0.355, p = 0.007) showed negative associations with CVD, while smoking rate (r = 0.183, p = 0.006) and whole milk (r = 0.113, p = 0.041) showed positive associations with CVD. The inverse association between dietary polyamines and CVD mortality revealed by the present study merits further evaluation.
Kuniyasu Soda; Yoshihiko Kano; Fumihiro Chiba
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Publication Detail:
Type:  Journal Article     Date:  2012-09-28
Journal Detail:
Title:  Global journal of health science     Volume:  4     ISSN:  1916-9736     ISO Abbreviation:  Glob J Health Sci     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101519495     Medline TA:  Glob J Health Sci     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  170-8     Citation Subset:  IM    
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