Document Detail

Food intake, sympathetic activity, and adrenal steroids.
MedLine Citation:
PMID:  8221149     Owner:  NLM     Status:  MEDLINE    
Food Intake is reciprocally related to the activity of sympathetic nerves to brown adipose tissue. This reciprocal or feedback relation is shown for hypothalamic lesions, drugs, and many peptides. These peptides also modulate intake of specific nutrients. Galanin and opioids increase fat intake, whereas enterostatin decreases fat intake. NPY increases carbohydrate intake and growth hormone releasing hormone decreases protein intake. The activity of the sympathetic nervous system is low in obesity and adrenalectomy reverses this decrease in sympathetic activity and reverses or stops the progression of obesity. One mechanism for this effect of adrenal steroids is through a transacting substance which is involved in steroid actions and the production of obesity.
G A Bray
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Brain research bulletin     Volume:  32     ISSN:  0361-9230     ISO Abbreviation:  Brain Res. Bull.     Publication Date:  1993  
Date Detail:
Created Date:  1993-12-07     Completed Date:  1993-12-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7605818     Medline TA:  Brain Res Bull     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  537-41     Citation Subset:  IM    
Department of Medicine, Louisiana State University, School of Medicine, Baton Rouge 70808-4124.
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MeSH Terms
Adrenal Glands / physiology*
Amino Acid Sequence
Eating / physiology*
Molecular Sequence Data
Norepinephrine / metabolism
Nutritional Status / physiology
Peptides / physiology
Steroids / physiology*
Sympathetic Nervous System / physiology*
Grant Support
Reg. No./Substance:
0/Peptides; 0/Steroids; 51-41-2/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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