Document Detail

Food-induced anaphylaxis: who, what, why, and where?
MedLine Citation:
PMID:  18751571     Owner:  NLM     Status:  MEDLINE    
Food-induced anaphylaxis is a leading cause of anaphylaxis treated in emergency departments and hospitals around the world. Peanuts, tree nuts, fish, and shellfish are the most commonly implicated foods. Food-induced anaphylaxis may occur in any age group and with any food. However, food-induced anaphylaxis fatalities disproportionately affect adolescents and young adults with peanut and tree nut allergy. Individuals who have both IgE-mediated food allergy and asthma are at a higher risk for food-induced anaphylaxis fatality. Delayed administration of epinephrine is also associated with fatal outcome. Often, in fatal reactions, the food allergen is unknowingly ingested away from home, in settings such as restaurants and schools. Although avoidance of food allergens is critical, timely administration of epinephrine is also of great importance in the treatment of food-induced anaphylaxis. Patients, families, and caregivers must be well educated regarding the signs, symptoms and risk factors for anaphylaxis. They must also be counseled on the importance of strict food avoidance of the implicated food allergens, compliance with having self-injectable epinephrine available at all times, and the importance of timely administration of epinephrine, even when cutaneous symptoms are lacking.
Ekta Shah; Jacqueline Pongracic
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric annals     Volume:  37     ISSN:  0090-4481     ISO Abbreviation:  Pediatr Ann     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-28     Completed Date:  2008-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0356657     Medline TA:  Pediatr Ann     Country:  United States    
Other Details:
Languages:  eng     Pagination:  536-41     Citation Subset:  IM    
Division of Allergy and Immunology, Children's Memorial Hospital, Northwestern University-McGaw Medical Center, Chicago, IL 60614, USA.
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MeSH Terms
Allergens / adverse effects*
Anaphylaxis / diagnosis,  epidemiology,  immunology*
Arachis hypogaea
Fish Products
Food Hypersensitivity / complications*,  epidemiology
Immunoglobulin E
Nut Hypersensitivity / immunology
Risk Factors
Severity of Illness Index
Time Factors
United States / epidemiology
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E

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