Document Detail

Food immediate-contact hypersensitivity (FICH) and elimination diet in young children with atopic dermatitis. Preliminary results in 107 children.
MedLine Citation:
PMID:  1476034     Owner:  NLM     Status:  MEDLINE    
In atopic dermatitis [AD], not only food consumption, but direct skin-contact too can provoke hypersensitivity reactions. We imitated food immediate-contact hypersensitivity [FICH] to cow's milk, egg, peanut or soy by a skin provocation test. This skin application food test [SAFT] was applied in 91 patients aged up to 5 years and suffering from AD, and in 16 healthy controls (all SAFT-negative). In the SAFT-positive patients (n = 61), FICH to egg was observed in 72%, to cow's milk in 47%, to peanut in 34% and soy in only 1 patient. SAFT and RAST scores correlated weakly. Nevertheless, many discrepancies between SAFT and RAST results were found. In 20 of the 61 (33%) patients with FICH, a flare-up in AD was noted at SAFT testing. Upon introducing dietary restrictions, AD improved impressively in 9 of 23 patients who could be followed up. FICH is an important symptom in children with AD and food allergy.
A P Oranje; R S Aarsen; P G Mulder; A W van Toorenenbergen; G Liefaard; P H Dieges
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica. Supplementum     Volume:  176     ISSN:  0365-8341     ISO Abbreviation:  Acta Derm Venereol Suppl (Stockh)     Publication Date:  1992  
Date Detail:
Created Date:  1993-02-03     Completed Date:  1993-02-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370311     Medline TA:  Acta Derm Venereol Suppl (Stockh)     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  41-4     Citation Subset:  IM    
Department of Dermato-Venereology, Erasmus University, Rotterdam, The Netherlands.
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MeSH Terms
Arachis hypogaea / adverse effects
Child, Preschool
Dermatitis, Allergic Contact / diagnosis,  diet therapy*,  immunology
Dermatitis, Atopic / diagnosis,  diet therapy*,  immunology
Eggs / adverse effects
Food Hypersensitivity / diagnosis,  diet therapy*,  immunology
Immunoglobulin E / analysis
Milk Hypersensitivity / diagnosis
Radioallergosorbent Test
Skin Tests
Reg. No./Substance:
37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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