| Food deprivation decreases the blood TRH concentration in the rat. | |
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MedLine Citation:
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PMID: 2836225 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Adult male rats were deprived of food for 1-6 days and the hypothalamo-pituitary axis in these rats was evaluated. Food deprivation caused a progressive decrease in TRH concentration in the peripheral blood with a concomitant reduction in the blood TSH level. No significant change was observed in the hypothalamic, extrahypothalamic or pancreatic TRH concentration between the control and starved groups. Starvation did not cause a significant change in the pituitary TRH receptors or the in vitro responsiveness of TSH to TRH. These data imply that the reduction in the blood TRH level may contribute in part to the decrease in the blood TSH level after food deprivation, but the origin of the blood TRH has remained to be determined. |
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Authors:
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M Mori; T Michimata; M Yamada; M Yamaguchi; T Iriuchijima; S Kobayashi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Experimental and clinical endocrinology Volume: 91 ISSN: 0232-7384 ISO Abbreviation: Exp. Clin. Endocrinol. Publication Date: 1988 Mar |
Date Detail:
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Created Date: 1988-07-14 Completed Date: 1988-07-14 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8302802 Medline TA: Exp Clin Endocrinol Country: GERMANY, EAST |
Other Details:
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Languages: eng Pagination: 97-104 Citation Subset: IM |
Affiliation:
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First Department of Internal Medicine, Gunma University, School of Medicine, Maebashi/Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Food Deprivation* Hypothalamus / metabolism Male Pancreas / metabolism Pituitary Gland, Anterior / drug effects, metabolism Rats Receptors, Neurotransmitter / metabolism Receptors, Thyrotropin-Releasing Hormone Thyrotropin / blood, metabolism Thyrotropin-Releasing Hormone / blood*, metabolism, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Neurotransmitter; 0/Receptors, Thyrotropin-Releasing Hormone; 24305-27-9/Thyrotropin-Releasing Hormone; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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