Document Detail


Food-dependent exercise-induced anaphylaxis induced by low dose aspirin therapy.
MedLine Citation:
PMID:  18089939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Food-dependent exercise-induced anaphylaxis (FDEIA) is a distinct form of common food allergy characteristically induced by a combination of causative food ingestion and physical exercise. Recent investigations have documented that aspirin consumption, in place of exercise, also induces allergic symptoms. CASE SUMMARY: A 63-year-old man began low dose aspirin therapy on September 2005. Since January 2006, he had repeated episodes of generalized urticaria and lost consciousness while he was exercising after eating wheat. He was strongly positive for omega-5 gliadin in a cap-system fluorescent enzyme immunoassay. Therefore, a diagnosis of wheat-dependent exercise-induced anaphylaxis was made. DISCUSSION: Patients with aspirin-provoked FDEIA have been reported previously as taking ordinary doses of aspirin for reducing pain, inflammation and fever. However, in our patient, low dose aspirin therapy for reducing cardiovascular risk possibility induced FDEIA. Growing numbers of elderly people take low doses of aspirin for prevention of cerebral or myocardial infarction. Therefore, physicians should remember that aspirin consumption, even at low doses, is a risk factor for FDEIA.
Authors:
Hiroko Fujii; Naotomo Kambe; Akihiro Fujisawa; Kunie Kohno; Eishin Morita; Yoshiki Miyachi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-03-01
Journal Detail:
Title:  Allergology international : official journal of the Japanese Society of Allergology     Volume:  57     ISSN:  1323-8930     ISO Abbreviation:  Allergol Int     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-02-26     Completed Date:  2008-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9616296     Medline TA:  Allergol Int     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  97-8     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
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MeSH Terms
Descriptor/Qualifier:
Anaphylaxis / chemically induced*,  diagnosis
Aspirin / adverse effects*,  therapeutic use
Exercise*
Gliadin / blood
Hematoma, Subdural / drug therapy,  surgery
Humans
Immunoglobulin E / blood,  immunology
Male
Middle Aged
Radioallergosorbent Test
Syncope / chemically induced
Urticaria / chemically induced
Vertebrobasilar Insufficiency / drug therapy
Wheat Hypersensitivity / etiology*
Chemical
Reg. No./Substance:
37341-29-0/Immunoglobulin E; 50-78-2/Aspirin; 9007-90-3/Gliadin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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