Document Detail

Food-dependent exercise-induced anaphylaxis--update and current data.
MedLine Citation:
PMID:  16711535     Owner:  NLM     Status:  MEDLINE    
Exercise-induced anaphylaxis (EIA) is defined as the onset of allergic symptoms during, or immediately after, exercise, the clinical signs being various degrees of urticaria, angioedema, respiratory and gastrointestinal signs and even anaphylactic shock. Food-dependent exercise-induced anaphylaxis (FDEIA) introduces food in the syndrome and is revealed by a chronological sequence in which food intake, followed by exercise, induces symptoms after a varying period. When the food intake and the exercise are independent of each other, there are no symptoms. FDEIA is not very frequent. Identifying the culprit food allergen depends on the patient's eating habits. Crustaceans and wheat flour are the two commonest but others foods can be implicated. The patho-physiology of FDEIA has not been clearly established but it appears to result from degranulation of mast cells. As with food allergy, FDEIA diagnosis is based on interview, skin and biological tests and challenge. For the clinical signs of allergy, antihistamines, corticosteroids and epinephrine may be administered. Prophylaxis aims to prevent a recurrence; the patient should be given an emergency kit to deal with any recurrent episode. After the food allergen has been identified, it should be avoided for at least 4 to 5 hours before any exercise.
E Beaudouin; J M Renaudin; M Morisset; F Codreanu; G Kanny; D A Moneret-Vautrin
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  European annals of allergy and clinical immunology     Volume:  38     ISSN:  1764-1489     ISO Abbreviation:  Eur Ann Allergy Clin Immunol     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-05-22     Completed Date:  2006-07-31     Revised Date:  2008-02-26    
Medline Journal Info:
Nlm Unique ID:  101466614     Medline TA:  Eur Ann Allergy Clin Immunol     Country:  France    
Other Details:
Languages:  eng     Pagination:  45-51     Citation Subset:  IM    
Department of Internal Medicine, Clinical Immunology and Allergology, University Hospital, Hôpital Central, Nancy, France.
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MeSH Terms
Allergens / adverse effects
Anaphylaxis / diagnosis,  drug therapy,  etiology*,  physiopathology
Anti-Allergic Agents / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / adverse effects
Asthma, Exercise-Induced / etiology*
Diagnosis, Differential
Drug Hypersensitivity / complications
Flushing / etiology
Follow-Up Studies
Food Hypersensitivity / complications*
Hypersensitivity, Immediate / complications
Meat / adverse effects
Prospective Studies
Pruritus / etiology
Seafood / adverse effects
Urticaria / etiology
Vegetables / adverse effects
Wheat Hypersensitivity / complications
Reg. No./Substance:
0/Allergens; 0/Anti-Allergic Agents; 0/Anti-Inflammatory Agents, Non-Steroidal

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