Document Detail


Food contamination by metals and pesticides in the European Union. Should we worry?
MedLine Citation:
PMID:  12052638     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The estimation of the risk associated with dietary intakes of heavy metals and pesticide residues by the consumer is a vital and integral part of regulatory processes. The exposure of the consumer is compared directly to the acceptable daily intake (ADI) for pesticides and to the tolerable daily intake (TDI) for heavy metals. The exposure is obtained using the basic equation: Exposure (mg/kg b.w./day)=Consumption (mg/kg b.w./day) x Residue (mg/kg). The establishment of the ADI and the TDI is based on the results of toxicological studies that involve the determination of the lowest-no-observed-adverse-effect level/10 (SF1) x10 (SF2), where SF corresponds to 'Safety Factor'. SF1 and SF2 account for interspecies and intraspecies variability, respectively. In order to evaluate the risk for the consumer, that is associated to the presence of heavy metals and pesticides in food, a review of the level of contamination in European countries has been made. The exposure of European consumers to lead, cadmium, arsenic and mercury is superior to the TDI. For pesticides, the first step is to compare the detected amount of residues of a specific pesticide to the maximum residue level (MRL) authorized in foodstuffs. If the residue level in food exceeds the MRL, the theoretical maximum daily intakes and the ADI have to be taken into account in order to assess the risk for the consumer.
Authors:
L Nasreddine; D Parent-Massin
Related Documents :
14594078 - Laser-induced breakdown spectroscopy for the detection of gunshot residues on the hands...
11848348 - Removal of organophosphate pesticides from wastewater by supercritical carbon dioxide e...
18941988 - Level of contamination and impact of pesticides in cupped oyster, crassostrea gigas, re...
19894148 - Screening for tetracycline residues in food products of animal origin in the state of k...
18550298 - Alternative sampling to establish the escherichia coli o157 status on beef cattle farms.
8100538 - Availability and utility of local fishes of shahjahanpur for mosquito control.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Toxicology letters     Volume:  127     ISSN:  0378-4274     ISO Abbreviation:  Toxicol. Lett.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-06-07     Completed Date:  2002-07-11     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7709027     Medline TA:  Toxicol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  29-41     Citation Subset:  IM    
Affiliation:
Lebanese Atomic Energy Commission/CNRS, Beirut, Lebanon, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cadmium / adverse effects,  analysis
European Union
Food Contamination / prevention & control,  statistics & numerical data*
Foodborne Diseases / etiology,  prevention & control
Humans
Lead / adverse effects,  analysis
Mercury / adverse effects,  analysis
Metals, Heavy / adverse effects,  analysis*
Pesticide Residues / adverse effects,  analysis*
Risk Assessment / statistics & numerical data
Risk Factors
Chemical
Reg. No./Substance:
0/Metals, Heavy; 0/Pesticide Residues; 7439-92-1/Lead; 7439-97-6/Mercury; 7440-43-9/Cadmium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Update of survey, regulation and toxic effects of mycotoxins in Europe.
Next Document:  Threshold of toxicological concern (TTC) in food safety assessment.