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Food allergy: mechanisms and therapeutics.
MedLine Citation:
PMID:  21943957     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The immunologic mechanisms responsible for the development of allergic sensitization rather than tolerance to foods are not well understood, although there have been a number of recent advances in our understanding of why some foods are inherently allergenic. In addition, the involvement of alternative routes of exposure that are not inherently tolerogenic may play a role in sensitization to foods. Although there are no currently accepted therapeutic approaches to food allergy, there are a number of approaches to treatment in preclinical or clinical trials. Here, we review selected findings published since 2009 that advance our understanding of mechanisms and new therapeutics for IgE-mediated food allergy.
Authors:
M Cecilia Berin; Scott Sicherer
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Publication Detail:
Type:  -     Date:  2011-9-21
Journal Detail:
Title:  Current opinion in immunology     Volume:  -     ISSN:  1879-0372     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8900118     Medline TA:  Curr Opin Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Ltd.
Affiliation:
Elliot and Roslyn Jaffe Food Allergy Institute, Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, New York, NY, USA.
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