Document Detail


Food allergy in children.
MedLine Citation:
PMID:  16272231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food allergy is being increasingly recognised with the highest prevalence being in preschool children. Pathogenesis varies so diagnosis rests on careful history and clinical examination, appropriate use of skin prick and serum-specific IgE testing, food challenge, and supervised elimination diets. A double blind placebo controlled food challenge is the gold standard diagnostic test. Avoidance of the allergenic food is the key towards successful management. IgE mediated food allergy may present as a potentially fatal anaphylactic reaction, and management consists of the appropriate use of adrenaline (epinephrine) and supportive measures. Sensitisation remains a key target for intervention. Disease modifying agents are currently under trial for managing difficult allergies. Management requires a multidisciplinary approach and follow up.
Authors:
V R Baral; J O'B Hourihane
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  81     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-07     Completed Date:  2006-03-23     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  693-701     Citation Subset:  IM    
Affiliation:
Infection, Inflammation and Repair Division, University of Southampton, UK.
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MeSH Terms
Descriptor/Qualifier:
Child
Diet
Food Hypersensitivity* / diagnosis,  etiology,  therapy
Forecasting
Humans
Immunoglobulin E / immunology
Referral and Consultation
Skin Tests
T-Lymphocytes, Helper-Inducer / immunology
Vaccination / adverse effects
Chemical
Reg. No./Substance:
37341-29-0/Immunoglobulin E
Comments/Corrections

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