Document Detail

Food allergies.
MedLine Citation:
PMID:  17298763     Owner:  NLM     Status:  In-Data-Review    
Food incompatibilities affect approximately 20% of the general population in Western countries. In about one quarter of the affected children and one tenth of affected adults, the incompatibility is based on an allergy, that is, on an immunologically generated incompatibility reaction. Gastrointestinal symptoms occur in a third of these cases. Food allergies are caused by IgE-dependent or IgE-independent immunologic reactions, which lead to an inflammatory reaction, in which mast cells, eosinophilic granulocytes, and other cells are involved. Both genetic and environmental causes are under consideration. New findings concerning the interaction between the innate immune system and intestinal microflora have generated innovative therapeutic concepts, including the use of probiotics to prevent food allergies. The development of recombinant allergens and varieties of allergens will improve diagnostic possibilities and bring new therapeutic options, such as hyposensitization and induction of immunologic tolerance. Food intolerances (nonimmunologic food incompatibilities often caused by specific enzyme deficiencies) must be diagnostically differentiated from food allergies.
Stephan C Bischoff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current treatment options in gastroenterology     Volume:  10     ISSN:  1092-8472     ISO Abbreviation:  Curr Treat Options Gastroenterol     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815941     Medline TA:  Curr Treat Options Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  34-43     Citation Subset:  -    
Stephan C. Bischoff, MD Department of Medicine, Nutritional Medicine and Prevention, (140b), University of Hohenheim, Stuttgart, Fruwirthstr. 12, 70593 Stuttgart, Germany.
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