Document Detail

Food additives intolerance: does it present as perennial rhinitis?
MedLine Citation:
PMID:  15090915     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: A case report published in 2001 raised the possibility that some patients with long-lasting 'nonallergic' perennial rhinitis might in effect have food additives intolerance. The recent literature published in English was reviewed to find controlled studies able to confirm this observation. RECENT FINDINGS: Two double-blind, placebo-controlled studies published between August 2002 and July 2003 confirmed the above observation. The prevalence of additives intolerance among individuals with 'nonallergic' perennial rhinitis is about 5%. The pathogenic mechanisms involved remain unclear. SUMMARY: Intolerance to food additives may sometimes present as perennial rhinitis. Clinicians should consider this possibility before they definitively dismiss patients as 'nonallergic'.
Riccardo Asero
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in allergy and clinical immunology     Volume:  4     ISSN:  1528-4050     ISO Abbreviation:  Curr Opin Allergy Clin Immunol     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-04-19     Completed Date:  2004-11-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100936359     Medline TA:  Curr Opin Allergy Clin Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-9     Citation Subset:  IM    
Head of the Allergy Unit, San Carlo Clinic, Paderno Dugnano (MI), Italy.
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MeSH Terms
Clinical Trials as Topic
Diagnosis, Differential
Food Additives / adverse effects*
Food Hypersensitivity / diagnosis,  etiology*
Rhinitis, Allergic, Perennial / diagnosis,  etiology
Reg. No./Substance:
0/Food Additives

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