Document Detail

Food addiction and obesity: evidence from bench to bedside.
MedLine Citation:
PMID:  20648909     Owner:  NLM     Status:  MEDLINE    
Obesity has become a major health problem and epidemic. However, much of the current debate has been fractious and etiologies of obesity have been attributed to eating behavior or fast food, personality issues, depression, addiction, or genetics. One of the interesting new hypotheses for epidemic obesity is food addiction, which is associated with both substance-related disorder and eating disorder. Accumulating evidences have shown that there are many shared neural and hormonal pathways as well as distinct differences that may help researchers find why certain individuals overeat and become obese. Functional neuroimaging studies have further revealed that good or great smelling, looking, tasting, and reinforcing food has characteristics similar to that of drugs of abuse. Many of the brain changes reported for hedonic eating and obesity are also seen in various forms of addictions. Most importantly, overeating and obesity may have an acquired drive like drug addiction with respect to motivation and incentive; craving, wanting, and liking occur after early and repeated exposures to stimuli. The acquired drive for great food and relative weakness of the satiety signal would cause an imbalance between the drive and hunger/reward centers in the brain and their regulation.
Yijun Liu; Karen M von Deneen; Firas H Kobeissy; Mark S Gold
Related Documents :
20648909 - Food addiction and obesity: evidence from bench to bedside.
22691819 - Determination of phytate, iron, zinc, calcium contents and their molar ratios in common...
10340819 - Sensory and hedonic associations with macronutrient and energy intakes of lean and obes...
22885269 - Aflatoxin contamination in stored rice variety pau 201 collected from punjab, india.
16817659 - The effect of trh and norepinephrine on the triglyceride droplets (tgd) in brown adipos...
14715209 - Self-reported overweight and obesity are not associated with concern about enough food ...
21291479 - Rapid and simple detection of the inva gene in salmonella spp. by isothermal target and...
25212369 - Analytical capabilities of inductively coupled plasma orthogonal acceleration time-of-f...
2742199 - Food-borne disease in hospitals: prevention in a changing food service environment.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of psychoactive drugs     Volume:  42     ISSN:  0279-1072     ISO Abbreviation:  J Psychoactive Drugs     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-22     Completed Date:  2010-08-26     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  8113536     Medline TA:  J Psychoactive Drugs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  133-45     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Appetitive Behavior
Brain / pathology,  physiopathology
Eating / physiology
Eating Disorders / genetics,  physiopathology
Food / adverse effects*
Obesity* / epidemiology,  etiology,  psychology
Prader-Willi Syndrome / physiopathology
Substance-Related Disorders* / complications,  etiology,  psychology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Prescription drug abuse: an epidemic dilemma.
Next Document:  Sweet preference, sugar addiction and the familial history of alcohol dependence: shared neural path...