| The Fontan circulation: who controls cardiac output? | |
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MedLine Citation:
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PMID: 19995891 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a Fontan circuit the mechanisms involved in control of cardiac output at rest and during exercise differ significantly from normal. The classical model presumes an unlimited preload which is not available in the Fontan circuit. This review critically analyses the role of contractility, heart rate, and afterload and highlights the importance of pulmonary vascular resistance (PVR) in determining adequate preload and, therefore, cardiac output in these patients. A conceptual model of the determinants of cardiac output in Fontan patients is presented. |
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Authors:
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Marc Gewillig; Stephen C Brown; Benedicte Eyskens; Ruth Heying; Javier Ganame; Werner Budts; Andre La Gerche; Matthias Gorenflo |
Publication Detail:
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Type: Journal Article; Review Date: 2009-12-07 |
Journal Detail:
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Title: Interactive cardiovascular and thoracic surgery Volume: 10 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-26 Completed Date: 2010-06-04 Revised Date: 2012-11-21 |
Medline Journal Info:
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Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England |
Other Details:
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Languages: eng Pagination: 428-33 Citation Subset: IM |
Affiliation:
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Paediatric and Congenital Cardiology, University Hospitals Leuven, Belgium. marc.gewillig@uzleuven.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Output* Exercise Fontan Procedure* / adverse effects Heart Defects, Congenital / physiopathology, surgery* Heart Rate Humans Models, Cardiovascular Myocardial Contraction Pulmonary Circulation Treatment Outcome Vascular Resistance |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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