Document Detail

The Fontan circulation: who controls cardiac output?
MedLine Citation:
PMID:  19995891     Owner:  NLM     Status:  MEDLINE    
In a Fontan circuit the mechanisms involved in control of cardiac output at rest and during exercise differ significantly from normal. The classical model presumes an unlimited preload which is not available in the Fontan circuit. This review critically analyses the role of contractility, heart rate, and afterload and highlights the importance of pulmonary vascular resistance (PVR) in determining adequate preload and, therefore, cardiac output in these patients. A conceptual model of the determinants of cardiac output in Fontan patients is presented.
Marc Gewillig; Stephen C Brown; Benedicte Eyskens; Ruth Heying; Javier Ganame; Werner Budts; Andre La Gerche; Matthias Gorenflo
Publication Detail:
Type:  Journal Article; Review     Date:  2009-12-07
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  10     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-26     Completed Date:  2010-06-04     Revised Date:  2012-11-21    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  428-33     Citation Subset:  IM    
Paediatric and Congenital Cardiology, University Hospitals Leuven, Belgium.
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MeSH Terms
Cardiac Output*
Fontan Procedure* / adverse effects
Heart Defects, Congenital / physiopathology,  surgery*
Heart Rate
Models, Cardiovascular
Myocardial Contraction
Pulmonary Circulation
Treatment Outcome
Vascular Resistance

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