Document Detail

Follow-up of twins: health, behaviour, speech, language outcomes and implications for parents.
MedLine Citation:
PMID:  16690232     Owner:  NLM     Status:  MEDLINE    
The introduction of assisted reproduction has resulted in a growing number of multiple births. These infants and their parents experience increased, and sometimes unique, medical and psychological risks when compared to singletons. Rates of maternal morbidity, fetal and infant mortality are increased in multiple pregnancies. Twins have a death rate four times higher than singletons and this figure is six times higher for triplets. The main reason is preterm and very preterm birth in multiples, resulting in low and very low birth weight children. Perinatal mortality and morbidity are also more elevated in monozygotic (MZ) twins as compared to dizygotic (DZ) twins. In addition to an increased risk of mortality, multiples have higher rates of morbidity, specifically cerebral palsy and mental subnormality. Language and speech delays are more pronounced in multiples, as are cognitive delays, motor development, behavioural problems and difficulties in parent-child interactions. Depression among parents of multiples is reported to be higher than those of singletons. This paper aims to critically appraise the literature regarding the aforementioned topics, including a comparison between the outcomes for iatrogenic and spontaneously conceived twins and to suggest areas for further research.
Alastair G Sutcliffe; Catherine Derom
Publication Detail:
Type:  Journal Article; Review     Date:  2006-05-11
Journal Detail:
Title:  Early human development     Volume:  82     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-12     Completed Date:  2006-08-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  379-86     Citation Subset:  IM    
Royal Free and University College Medical School, University College London, Department of Community Child Health, Royal Free Campus, UK.
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MeSH Terms
Child Development / physiology*
Child Welfare*
Child, Preschool
Follow-Up Studies
Infant Behavior* / physiology,  psychology
Infant, Newborn
Parent-Child Relations*
Twins / physiology*,  psychology
Verbal Behavior / physiology*

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