| Follow-up study of two-year-olds born at very low gestational age in Estonia. | |
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MedLine Citation:
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PMID: 23176138 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIM: To study very low gestational age (VLGA, <32 weeks) infants at two years of age and to identify the predictors of adverse outcomes. METHODS: A population-based cohort of 155 surviving VLGA infants born in Estonia in 2007 was followed up and compared with a matched full-term control group. A logistic regression model was used to test associations between risk factors and adverse outcomes. RESULTS: No impairment was found in 60% of the VLGA infants. Neurodevelopmental impairment was noted in 12% of VLGA infants, with 8% of the infants affected by cerebral palsy without independent walking, 5% with cognitive delay, 10% with language delay, and 1% with hearing impairment. The differences between preterm and full-term infants in terms of the mean Cognitive, Language, and Motor Composite Scores assessed using the Bayley-III scales were in excess of 0.5 SD. Somatic growth delay was a significant problem among preterm infants. The existence of severe neonatal cerebral lesions was the most significant predictor of adverse outcomes. CONCLUSION: In all domains studied, adverse conditions were more prevalent among VLGA infants than among the full-term control group. Efforts to reduce neonatal morbidity in preterm infants should be a key priority for health care in Estonia. ©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica. |
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Authors:
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Liis Toome; Heili Varendi; Mairi Männamaa; Mari-Anne Vals; Triinu Tänavsuu; Anneli Kolk |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-23 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: - ISSN: 1651-2227 ISO Abbreviation: Acta Paediatr. Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica. |
Affiliation:
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Department of Paediatrics, University of Tartu, Tartu, Estonia; Clinic of Paediatrics, Tallinn Children's Hospital, Tallinn, Estonia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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