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Follow-up study of two-year-olds born at very low gestational age in Estonia.
MedLine Citation:
PMID:  23176138     Owner:  NLM     Status:  Publisher    
AIM: To study very low gestational age (VLGA, <32 weeks) infants at two years of age and to identify the predictors of adverse outcomes. METHODS: A population-based cohort of 155 surviving VLGA infants born in Estonia in 2007 was followed up and compared with a matched full-term control group. A logistic regression model was used to test associations between risk factors and adverse outcomes. RESULTS: No impairment was found in 60% of the VLGA infants. Neurodevelopmental impairment was noted in 12% of VLGA infants, with 8% of the infants affected by cerebral palsy without independent walking, 5% with cognitive delay, 10% with language delay, and 1% with hearing impairment. The differences between preterm and full-term infants in terms of the mean Cognitive, Language, and Motor Composite Scores assessed using the Bayley-III scales were in excess of 0.5 SD. Somatic growth delay was a significant problem among preterm infants. The existence of severe neonatal cerebral lesions was the most significant predictor of adverse outcomes. CONCLUSION: In all domains studied, adverse conditions were more prevalent among VLGA infants than among the full-term control group. Efforts to reduce neonatal morbidity in preterm infants should be a key priority for health care in Estonia. ©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica.
Liis Toome; Heili Varendi; Mairi Männamaa; Mari-Anne Vals; Triinu Tänavsuu; Anneli Kolk
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-23
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica.
Department of Paediatrics, University of Tartu, Tartu, Estonia; Clinic of Paediatrics, Tallinn Children's Hospital, Tallinn, Estonia.
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