Document Detail

Follow-up of patients with suspected multiple sclerosis: a clinical and electrophysiological study.
MedLine Citation:
PMID:  7131014     Owner:  NLM     Status:  MEDLINE    
We re-examined 21 patients with suspected multiple sclerosis, seven classified as probable and 14 as possible cases. At the first investigation all patients but two had abnormal visual evoked potentials and somatosensory evoked potentials, or both. All but three had an increased intracerebral production of immunoglobulin G expressed by the cerebrospinal fluid IgG index. At follow-up two to four years later, 13 of 16 patients (81%) in whom both evoked potentials and IgG index were abnormal initially had entered into a higher multiple sclerosis diagnostic class. In the five patients in whom either evoked potentials or IgG index were normal the original diagnosis was unchanged.
J Bøttcher; W Trojaborg
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  45     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  809-14     Citation Subset:  IM    
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MeSH Terms
Diagnosis, Differential
Electric Stimulation
Evoked Potentials, Somatosensory
Evoked Potentials, Visual
Follow-Up Studies
Immunoglobulin G / cerebrospinal fluid
Middle Aged
Multiple Sclerosis / diagnosis*,  immunology
Photic Stimulation
Tibial Nerve / physiopathology
Reg. No./Substance:
0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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