Document Detail


Follow-up in 103 patients with catecholamine-secreting tumours.
MedLine Citation:
PMID:  9737887     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
103 patients from a group of 115 patients with catecholamine secreting tumours were reinvestigated 7.0 +/- 4.9 years following surgery. Throughout the follow-up period 15 patients had died. In four of them death was definitively, in seven subjects possibly associated to the primary endocrine disorder. Following surgery improvement of general well-being was documented in 85% of the patients. Hypertension was corrected in 61 %, but 26% of the patients remained hypertensive and symptoms of hypotension like orthostasis developed in 24%. A significant increase in weight (> 5 kg) was observed in 26% of the subjects throughout the follow-up period, but did not result in a higher prevalence of diabetes mellitus which had to be treated in 16% of the patients before and only 14% following surgery. However, palpitations, increased sweating and headache persisted in 16%, 17% and 12% of the patients, respectively. Symptoms of cardiac insufficiency developed in 32%. Persistent discomfort related to the scar was reported by 55% of the patients following lumbar surgery and by 30% of the subjects that were operated on via a transabdominal approach. Hence we conclude that surgery of catecholamine-secreting tumours results in an improvement of health and well-being in most subjects according to objective criteria as well as to the judgement of the patients themselves.
Authors:
H Kreft; G F Scheumann; A von zur Mühlen; T H Schürmeyer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of medical research     Volume:  3     ISSN:  0949-2321     ISO Abbreviation:  Eur. J. Med. Res.     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-11-17     Completed Date:  1998-11-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9517857     Medline TA:  Eur J Med Res     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  413-8     Citation Subset:  IM    
Affiliation:
Abt. Endokrinologie und Stoffwechsel, FPP, Universität Trier, Friedrich Wilhelm-Str. 29, D-54290 Trier, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Catecholamines / secretion*
Endocrine Gland Neoplasms / physiopathology,  secretion*,  surgery
Female
Follow-Up Studies
Humans
Male
Middle Aged
Chemical
Reg. No./Substance:
0/Catecholamines

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